Table 3. Relationship among chemotherapy efficacy, clinicopathological features, and EphA2 expression (χ² test).

Parameters	n	CR+PR	Response rate (%)	P-value
Age (years)
<60	32	13	59.37	0.172
≥60	88	49	55.68
Gender
male	61	30	49.18	0.144
Female	59	32	54.24
Size of tumor
<5 cm	64	37	57.81	0.115
>5 cm	56	25	44.64
ECOG score
0-1	58	36	62.07	0.100
2	62	26	41.94
Histologic type
Well and moderate	44	32	72.72	0.032
Poor and undifferentiated	76	30	39.47
CEA (ng/mL)
<5	29	20	68.96	0.081
≥5	91	42	46.15
EphA2
+	73	25	34.24	0.007
-	47	37	78.72

ECOG: Eastern Cooperative Oncology Group; CEA: carcino-embryonic antigen; Eph: erythropoietin-producing human hepatocellular carcinoma; CR: complete remission; PR: partial remission.