Figure 2. Inhibition of YB-1suppresses migration of lung adenocarcinoma cells.

(A,B) Wound healing assay of lung adenocarcinoma cells in the YB-1-silenced cells (shYB1-1 and shYB1-2: YB-1-silenced A549 cells; shYB1-3 and shYB1-4: YB-1-silenced H1299 cells) and their corresponding control cells. The distance from the wound edge was calculated with corresponding summary (right panel). (C,D) Transwell assay in lung adenocarcinoma cells in the YB-1-silenced cells and their corresponding control cells. Columns were averaged from three independent experiments. * P<0.05, **P<0.01,*** P<0.005, two-tailed Student's T-tests. Error bars represent mean±s.d. Scale bars, 100 μm (A,B), 50 μm (C,D).