Figure 1. Mutational profile of tumor genomic alterations per patient (n=25).

The alterations are function-altering variants (SNV, insertion or deletion) and copy number variants (copy gain, heterozygous or homozygous deletion) detected per patient on the horizontal axis and per gene on the vertical axis for the entire PCNSL cohort. MYD88 and CDKN2A were the most commonly affected genes with regard to SNV and heterozygous or homozygous deletions, respectively.