Table 1. Description and Probe sequence for 6 SNPs used for Taqman fluorescence probe analysis.
SNP ID | Chromosome | Functional Consequence | Major/ minor alleles | Nucleotide sequences/ Probe sequence |
---|---|---|---|---|
SORL1 | ||||
rs689021 | 11:121500411 | Intron variant | T/C | Forward: ACGTTGGATGACCTTACAGATGATGCAGCC Reverse: ACGTTGGATGGGCCATAGTTTCCTAGCATC |
rs3824966 | 11:121577474 | Intron variant | G/C | Forward: ACGTTGGATGCCAAGCTAATTCTCAGAGCC Reverse: ACGTTGGATGTTGACAGCACTCATCCGTTC |
rs1784933 | 11:121618707 | Intron variant | G/A | Forward: ACGTTGGATGTTTGAAGCAGTTCCAGGGTC Reverse: ACGTTGGATGGAATGGAAGAGGACATCAGC |
PPARG | ||||
rs709158 | 3:12421677 | Intron variant | A/G | 5’-AGATACGGGGGAGGAAATTCACTGG[A/G] TTTTACAATATATTTTTCAAGGCAA-3’ |
rs10865710 | 3:12311699 | Intron variant, upstream variant 2KB | C/G | 5’-TTGGCATTAGATGCTGTTTTGTCTT[C/G] ATGGAAAATACAGCTATTCTAGGAT-3’ |
rs1805192 | 3:12379739 | Missense | C/G | 5’-ACCTCAGACAGATTGTCACGGAACA[C/T] GTGCAGCTACTGCAGGTGATCAAGA-3’ |