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. 2017 Jun 1;8(30):48563–48574. doi: 10.18632/oncotarget.18335

Figure 2. IL-33 deficiency moderately affects systemic insulin sensitivity.

Figure 2

A. Variation of body weight after 12 weeks of SD HFD in WT and IL-33 KO mice. B. Insulin tolerance test conducted at week 9 in IL-33 KO-HFD and WT-HFD mice. Mice received an i.p. injection of 0.5U/kg insulin after a four-hour fast. Blood glucose concentrations were measured 0, 30, 60 and 120 minutes after injection. C. Relative mRNA transcript levels of the lipogenic factor PPAR-γ in the liver. The y-axis values represent the induction of PPAR-γ relative to control (SD-fed mice) after normalization using 18S. Statistical analysis of the data was performed using the non-parametric Mann-Whitney U-test. Differences were considered to be significant for p < 0.05 and are indicated as follows: *p < 0.05, **p < 0.01, ***p < 0.001, ns: non-significant.