Skip to main content
. 2017 Apr 11;8(30):49053–49063. doi: 10.18632/oncotarget.17041

Figure 5. Effects of ERBB4, IRF2 and CXCR4 knockdown CRI critical pathway and cytokines.

Figure 5

(A) Western blot of ERBB4 protein expression in TE11 cells transfected with pGLV3/shXIAP or pGLV3/shcontrol, respectively. (B) Western blot of IRF2 protein expression in TE11 cells stably transfected with pGLV3/shXIAP or pGLV3/shcontrol, respectively. (C) Western blot of CXCR4 protein expression in TE11 cells stably transfected with pGLV3/shXIAP or pGLV3/shcontrol, respectively. (D) Effect of down-regulation of ERBB4, IRF2 and CXCR4 together on cytokines (IL-6, IL-23, and TNF-β) expression. (E) Effect of down-regulation of ERBB4, IRF2 and CXCR4 together on protein expression of NF-κB, STAT3, and HIF-1α. U6 or β-actin was used as an internal control. Each experiment was performed at least in triplicate. *P < 0.05, **P < 0.01 vs control.