Table 1. Relationship between miR-196a-3p expression and clinicalpathologic variables of breast cancer patients.
Parameters | Number of cases | miR-196a-3p expression | P value | |
---|---|---|---|---|
Low (52) | High (60) | |||
Age(years) | ||||
<50 | 49 | 18 | 31 | 0.07 |
≥50 | 63 | 34 | 29 | |
Tumor size(cm) | ||||
<2 | 63 | 25 | 38 | 0.105 |
≥2 | 49 | 27 | 22 | |
TNM stage | ||||
I+II | 70 | 24 | 46 | 0.001* |
III | 42 | 28 | 14 | |
Differentiation grade | ||||
G1+G2 | 84 | 34 | 50 | 0.029* |
G3 | 28 | 18 | 10 | |
Lymph node metastasis | ||||
Yes | 56 | 33 | 23 | 0.008* |
No | 56 | 19 | 37 | |
ER status | ||||
Negative | 58 | 32 | 26 | 0.054 |
Positive | 54 | 20 | 34 | |
PR status | ||||
Negative | 57 | 30 | 27 | 0.18 |
Positive | 55 | 22 | 33 | |
HER2 status | ||||
Negative | 57 | 31 | 26 | 0.086 |
Positive | 55 | 21 | 34 |
* P < 0.05 was considered significant.