Table 3. Diagnostic performance of intravoxel incoherent motion magnetic resonance parameters in distinguishing human epidermal growth factor receptor 2 (HER2) positive gastric cancers from HER2 negative ones.
| Parameters | Cut-off | Sensitivity | Specificity | AUC | P value |
|---|---|---|---|---|---|
| ADC | 1.321 | 0.900 | 0.651 | 0.733 | 0.023† |
| D | 1.123 | 0.800 | 0.721 | 0.762 | 0.011† |
| f | 0.119 | 0.800 | 0.395 | 0.510 | 0.919 |
| D* | 52.352 | 0.500 | 0.860 | 0.670 | 0.097 |
Note: ADC, apparent diffusion coefficient; D, pure diffusion coefficient; f, perfusion related fraction; D*, pseudo diffusion coefficient; AUC, area under the receiver operating characteristic (ROC) curve. The cut-off values of ADC, D and D* are in unit of × 10−3 mm2/sec. †P < 0.05 with ROC analysis.