Table 6. Mixed evidence of recurrence for different treatments.
Ble+Cis+Ifo | Ble+Cis+MitoC+Vbl | Ble+Cis+Vbl | Ble+Cis+Vcr | Cis | Cis+Doc | Cis+Epi | Cis+Flu | Cis+Ifo | Cis+Ifo+Pac | Cis+Methotrexate | Cis+Mitolactol | Cis+Topotecan | Cis+Vcr | Epi | Flu | Cis+Flu+Hyd | Flu+MitoC | Hyd | Placebo | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ble+Cis+Ifo | Ble+Cis+Ifo | 1.73 (0.33, 8.40) | 1.68 (0.48, 5.90) | 1.77 (0.53, 5.58) | 0.85 (0.33, 2.06) | 0.51 (0.11, 2.12) | 1.72 (0.44, 6.58) | 0.65 (0.25, 1.59) | 0.24 (0.07, 0.74) | 0.22 (0.04, 1.09) | 1.18 (0.23, 5.85) | 0.91 (0.17, 5.27) | 0.61 (0.13, 2.89) | 1.50 (0.37, 5.48) | 0.77 (0.18, 2.93) | 0.73 (0.25, 2.00) | 0.62 (0.16, 2.13) | 0.56 (0.15, 1.92) | 1.02 (0.33, 2.68) | 1.43 (0.61, 3.20) |
Ble+Cis+MitoC+Vbl | 0.58 (0.12, 2.99) | Ble+Cis+MitoC+Vbl | 0.98 (0.19, 5.19) | 1.04 (0.21, 5.24) | 0.49 (0.11, 2.13) | 0.30 (0.05, 1.81) | 1.01 (0.17, 5.95) | 0.38 (0.09, 1.61) | 0.14 (0.02, 0.86) | 0.13 (0.02, 1.08) | 0.69 (0.10, 4.76) | 0.53 (0.07, 5.08) | 0.36 (0.05, 2.47) | 0.87 (0.16, 4.95) | 0.44 (0.08, 2.62) | 0.42 (0.09, 1.93) | 0.36 (0.07, 1.90) | 0.33 (0.06, 1.74) | 0.59 (0.13, 2.53) | 0.84 (0.21, 3.32) |
Ble+Cis+Vbl | 0.60 (0.17, 2.10) | 1.02 (0.19, 5.34) | Ble+Cis+Vbl | 1.06 (0.29, 3.76) | 0.50 (0.17, 1.46) | 0.30 (0.06, 1.42) | 1.02 (0.25, 4.33) | 0.38 (0.13, 1.10) | 0.14 (0.03, 0.65) | 0.13 (0.02, 0.87) | 0.70 (0.13, 3.75) | 0.54 (0.09, 3.82) | 0.37 (0.07, 1.85) | 0.89 (0.20, 3.71) | 0.46 (0.10, 1.99) | 0.43 (0.13, 1.36) | 0.37 (0.09, 1.44) | 0.33 (0.08, 1.28) | 0.60 (0.19, 1.78) | 0.85 (0.33, 2.19) |
Ble+Cis+Vcr | 0.56 (0.18, 1.88) | 0.97 (0.19, 4.83) | 0.95 (0.27, 3.39) | Ble+Cis+Vcr | 0.48 (0.18, 1.25) | 0.29 (0.06, 1.27) | 0.97 (0.25, 3.76) | 0.37 (0.14, 0.94) | 0.14 (0.03, 0.57) | 0.12 (0.02, 0.78) | 0.67 (0.13, 3.31) | 0.51 (0.09, 3.56) | 0.34 (0.07, 1.69) | 0.84 (0.21, 3.27) | 0.43 (0.10, 1.70) | 0.41 (0.14, 1.17) | 0.35 (0.09, 1.27) | 0.31 (0.09, 1.12) | 0.57 (0.19, 1.53) | 0.81 (0.35, 1.87) |
Cis | 1.18 (0.48, 3.05) | 2.03 (0.47, 8.74) | 1.99 (0.68, 5.73) | 2.10 (0.80, 5.45) | Cis | 0.60 (0.19, 1.86) | 2.05 (0.64, 6.67) | 0.76 (0.44, 1.31) | 0.29 (0.09, 0.89) | 0.26 (0.05, 1.31) | 1.40 (0.32, 6.03) | 1.07 (0.23, 6.03) | 0.73 (0.21, 2.59) | 1.77 (0.55, 5.67) | 0.91 (0.27, 3.02) | 0.85 (0.42, 1.71) | 0.74 (0.27, 1.84) | 0.66 (0.23, 1.89) | 1.21 (0.59, 2.18) | 1.69 (1.06, 2.68) |
Cis+Doc | 1.97 (0.47, 8.71) | 3.38 (0.55, 21.43) | 3.35 (0.71, 16.05) | 3.51 (0.79, 15.93) | 1.68 (0.54, 5.27) | Cis+Doc | 3.39 (0.66, 18.11) | 1.28 (0.36, 4.55) | 0.48 (0.10, 2.47) | 0.44 (0.06, 3.23) | 2.34 (0.37, 14.68) | 1.81 (0.26, 14.25) | 1.22 (0.22, 6.64) | 2.97 (0.57, 15.12) | 1.52 (0.29, 8.02) | 1.44 (0.37, 5.51) | 1.23 (0.26, 5.29) | 1.12 (0.23, 5.28) | 2.01 (0.50, 7.15) | 2.84 (0.82, 9.70) |
Cis+Epi | 0.58 (0.15, 2.27) | 0.99 (0.17, 5.72) | 0.98 (0.23, 4.08) | 1.03 (0.27, 4.03) | 0.49 (0.15, 1.55) | 0.29 (0.06, 1.51) | Cis+Epi | 0.38 (0.11, 1.19) | 0.14 (0.03, 0.68) | 0.13 (0.02, 0.91) | 0.68 (0.12, 3.88) | 0.53 (0.08, 3.96) | 0.36 (0.06, 1.93) | 0.87 (0.19, 3.85) | 0.45 (0.09, 2.03) | 0.42 (0.11, 1.45) | 0.36 (0.08, 1.52) | 0.33 (0.07, 1.36) | 0.59 (0.16, 1.89) | 0.83 (0.28, 2.38) |
Cis+Flu | 1.54 (0.63, 4.03) | 2.65 (0.62, 11.16) | 2.61 (0.91, 7.46) | 2.73 (1.07, 7.22) | 1.31 (0.76, 2.26) | 0.78 (0.22, 2.77) | 2.66 (0.84, 8.77) | Cis+Flu | 0.38 (0.11, 1.24) | 0.34 (0.07, 1.83) | 1.83 (0.42, 7.83) | 1.41 (0.28, 8.31) | 0.95 (0.24, 3.65) | 2.30 (0.72, 7.41) | 1.18 (0.36, 3.93) | 1.11 (0.51, 2.43) | 0.96 (0.33, 2.58) | 0.86 (0.29, 2.49) | 1.57 (0.77, 2.83) | 2.21 (1.40, 3.53) |
Cis+Ifo | 4.08 (1.35, 13.49) | 7.12 (1.17, 42.43) | 6.91 (1.55, 31.52) | 7.30 (1.74, 30.66) | 3.47 (1.13, 11.09) | 2.06 (0.41, 10.46) | 7.10 (1.48, 35.27) | 2.65 (0.81, 9.06) | Cis+Ifo | 0.90 (0.30, 2.89) | 4.87 (0.78, 30.22) | 3.71 (0.92, 18.13) | 2.51 (0.46, 13.93) | 6.09 (1.28, 29.86) | 3.15 (0.62, 15.87) | 2.96 (0.81, 11.07) | 2.53 (0.57, 10.86) | 2.29 (0.51, 10.21) | 4.14 (1.12, 14.63) | 5.86 (1.90, 19.01) |
Cis+Ifo+Pac | 4.53 (0.92, 22.95) | 7.72 (0.93, 64.19) | 7.58 (1.15, 48.69) | 8.00 (1.27, 47.80) | 3.81 (0.76, 18.89) | 2.28 (0.31, 16.11) | 7.78 (1.09, 54.27) | 2.92 (0.55, 14.99) | 1.11 (0.35, 3.31) | Cis+Ifo+Pac | 5.36 (0.61, 44.30) | 4.10 (0.69, 27.85) | 2.75 (0.35, 20.72) | 6.67 (0.94, 47.95) | 3.43 (0.48, 25.04) | 3.25 (0.58, 18.35) | 2.79 (0.43, 16.82) | 2.52 (0.39, 16.28) | 4.61 (0.79, 23.56) | 6.47 (1.28, 31.85) |
Cis+Methotrexate | 0.85 (0.17, 4.28) | 1.45 (0.21, 10.09) | 1.42 (0.27, 7.68) | 1.49 (0.30, 7.58) | 0.72 (0.17, 3.11) | 0.43 (0.07, 2.67) | 1.46 (0.26, 8.52) | 0.55 (0.13, 2.36) | 0.21 (0.03, 1.28) | 0.19 (0.02, 1.63) | Cis+Methotrexate | 0.78 (0.10, 6.92) | 0.51 (0.08, 3.57) | 1.26 (0.22, 7.11) | 0.65 (0.11, 3.91) | 0.61 (0.13, 2.83) | 0.52 (0.09, 2.79) | 0.47 (0.09, 2.50) | 0.86 (0.19, 3.69) | 1.21 (0.31, 4.82) |
Cis+Mitolactol | 1.09 (0.19, 5.90) | 1.90 (0.20, 15.11) | 1.85 (0.26, 11.69) | 1.97 (0.28, 11.13) | 0.93 (0.17, 4.32) | 0.55 (0.07, 3.78) | 1.89 (0.25, 12.86) | 0.71 (0.12, 3.55) | 0.27 (0.06, 1.09) | 0.24 (0.04, 1.46) | 1.29 (0.14, 10.22) | Cis+Mitolactol | 0.67 (0.08, 4.90) | 1.64 (0.21, 10.64) | 0.84 (0.10, 5.77) | 0.79 (0.12, 4.18) | 0.68 (0.09, 4.06) | 0.62 (0.08, 3.85) | 1.11 (0.17, 5.60) | 1.58 (0.27, 7.52) |
Cis+Topotecan | 1.63 (0.35, 7.93) | 2.79 (0.41, 19.03) | 2.74 (0.54, 14.35) | 2.90 (0.59, 14.27) | 1.37 (0.39, 4.81) | 0.82 (0.15, 4.47) | 2.80 (0.52, 15.94) | 1.05 (0.27, 4.13) | 0.40 (0.07, 2.18) | 0.36 (0.05, 2.88) | 1.94 (0.28, 12.66) | 1.50 (0.20, 12.39) | Cis+Topotecan | 2.41 (0.43, 13.44) | 1.25 (0.22, 6.98) | 1.18 (0.28, 4.94) | 1.01 (0.20, 4.66) | 0.90 (0.18, 4.57) | 1.65 (0.39, 6.37) | 2.33 (0.61, 8.94) |
Cis+Vcr | 0.67 (0.18, 2.70) | 1.16 (0.20, 6.39) | 1.12 (0.27, 4.91) | 1.19 (0.31, 4.66) | 0.57 (0.18, 1.82) | 0.34 (0.07, 1.75) | 1.15 (0.26, 5.20) | 0.43 (0.13, 1.39) | 0.16 (0.03, 0.78) | 0.15 (0.02, 1.06) | 0.79 (0.14, 4.46) | 0.61 (0.09, 4.77) | 0.41 (0.07, 2.32) | Cis+Vcr | 0.52 (0.11, 2.40) | 0.49 (0.14, 1.68) | 0.42 (0.09, 1.74) | 0.38 (0.09, 1.62) | 0.68 (0.19, 2.18) | 0.96 (0.33, 2.83) |
Epi | 1.30 (0.34, 5.48) | 2.25 (0.38, 13.27) | 2.19 (0.50, 9.60) | 2.30 (0.59, 9.59) | 1.10 (0.33, 3.66) | 0.66 (0.12, 3.45) | 2.24 (0.49, 10.59) | 0.85 (0.25, 2.78) | 0.32 (0.06, 1.60) | 0.29 (0.04, 2.07) | 1.54 (0.26, 9.12) | 1.19 (0.17, 9.58) | 0.80 (0.14, 4.63) | 1.93 (0.42, 9.12) | Epi | 0.94 (0.26, 3.39) | 0.81 (0.18, 3.45) | 0.72 (0.16, 3.21) | 1.32 (0.36, 4.47) | 1.87 (0.62, 5.71) |
Flu | 1.37 (0.50, 4.04) | 2.38 (0.52, 11.00) | 2.34 (0.73, 7.50) | 2.46 (0.85, 7.23) | 1.17 (0.59, 2.38) | 0.69 (0.18, 2.71) | 2.38 (0.69, 8.71) | 0.90 (0.41, 1.96) | 0.34 (0.09, 1.24) | 0.31 (0.05, 1.73) | 1.64 (0.35, 7.77) | 1.26 (0.24, 8.06) | 0.85 (0.20, 3.58) | 2.06 (0.59, 7.20) | 1.06 (0.30, 3.92) | Flu | 0.86 (0.26, 2.69) | 0.77 (0.29, 2.11) | 1.41 (0.56, 3.16) | 1.98 (1.03, 3.91) |
Cis+Flu+Hyd | 1.61 (0.47, 6.28) | 2.79 (0.53, 15.34) | 2.72 (0.69, 11.11) | 2.85 (0.79, 11.08) | 1.36 (0.54, 3.74) | 0.81 (0.19, 3.82) | 2.79 (0.66, 12.37) | 1.04 (0.39, 3.05) | 0.39 (0.09, 1.76) | 0.36 (0.06, 2.34) | 1.91 (0.36, 10.73) | 1.47 (0.25, 10.55) | 0.99 (0.21, 5.00) | 2.39 (0.57, 10.76) | 1.24 (0.29, 5.68) | 1.16 (0.37, 3.81) | Cis+Flu+Hyd | 0.90 (0.24, 3.75) | 1.64 (0.61, 4.13) | 2.30 (0.88, 6.50) |
Flu+MitoC | 1.78 (0.52, 6.68) | 3.07 (0.57, 16.69) | 3.02 (0.78, 11.79) | 3.18 (0.90, 11.66) | 1.51 (0.53, 4.27) | 0.90 (0.19, 4.32) | 3.06 (0.74, 13.35) | 1.16 (0.40, 3.43) | 0.44 (0.10, 1.95) | 0.40 (0.06, 2.58) | 2.11 (0.40, 11.57) | 1.62 (0.26, 11.85) | 1.11 (0.22, 5.51) | 2.66 (0.62, 11.38) | 1.38 (0.31, 6.10) | 1.29 (0.47, 3.44) | 1.11 (0.27, 4.24) | Flu+MitoC | 1.82 (0.56, 5.36) | 2.56 (0.95, 6.80) |
Hyd | 0.98 (0.37, 3.02) | 1.69 (0.40, 7.94) | 1.67 (0.56, 5.31) | 1.75 (0.66, 5.30) | 0.83 (0.46, 1.70) | 0.50 (0.14, 2.00) | 1.69 (0.53, 6.32) | 0.64 (0.35, 1.29) | 0.24 (0.07, 0.89) | 0.22 (0.04, 1.27) | 1.16 (0.27, 5.40) | 0.90 (0.18, 5.81) | 0.61 (0.16, 2.58) | 1.46 (0.46, 5.29) | 0.76 (0.22, 2.80) | 0.71 (0.32, 1.79) | 0.61 (0.24, 1.63) | 0.55 (0.19, 1.79) | Hyd | 1.41 (0.81, 2.73) |
Placebo | 0.70 (0.31, 1.64) | 1.19 (0.30, 4.73) | 1.18 (0.46, 3.05) | 1.24 (0.54, 2.85) | 0.59 (0.37, 0.94) | 0.35 (0.10, 1.23) | 1.20 (0.42, 3.60) | 0.45 (0.28, 0.71) | 0.17 (0.05, 0.53) | 0.15 (0.03, 0.78) | 0.83 (0.21, 3.27) | 0.63 (0.13, 3.66) | 0.43 (0.11, 1.64) | 1.04 (0.35, 3.03) | 0.54 (0.18, 1.61) | 0.51 (0.26, 0.97) | 0.43 (0.15, 1.13) | 0.39 (0.15, 1.05) | 0.71 (0.37, 1.24) | Placebo |