Table 2. Univariate analysis of prognostic factors for locoregional recurrence-free survival.
Characteristic | Entire cohort | Without PMRT | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age, years (< 40 vs. ≥ 40) | 0.553 | 0.343-0.891 | 0.015 | 0.44 | 0.272-0.71 | 0.001 |
LNR (≤0.2 vs. >0.2) | 2.387 | 1.367-4.167 | 0.002 | 2.519 | 1.44-4.405 | 0.001 |
Positive lymph nodes N(1-2 vs. 3) | 1.39 | 0.869-2.226 | 0.170 | 1.65 | 1.023-2.666 | 0.040 |
Tumor size (T1 vs. T2) | 1.167 | 0.564-2.417 | 0.677 | 1.23 | 0.593-2.549 | 0.588 |
Lymphatic invasion(negative vs. positive) | 0.813 | 0.375-1.763 | 0.600 | 0.803 | 0.37-1.744 | 0.580 |
Menopausal status (Pre vs. Post) | 1.5 | 0.792-2.838 | 0.213 | 1.198 | 0.632-2.274 | 0.580 |
Molecule classification | ||||||
(luminal B vs. luminal A) | 1.382 | 0.592-3.225 | 0.454 | 1.415 | 0.606-3.307 | 0.422 |
(her2-enriched vs. luminal A) | 2.089 | 1.573-2.773 | 0.001 | 2.065 | 1.543-2,764 | 0.001 |
(triple negative vs. luminal A) | 1.152 | 0.946-1.403 | 0.159 | 1.154 | 0.947-1.406 | 0.156 |
PMRT (yes vs. no) | 0.155 | 0.038-0.629 | 0.009 |
PMRT, postmastectomy radiotherapy; LNR, lymph node ratio; HR, hazard ratio; CI, confidence interval.