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. 2017 May 17;8(30):49773–49782. doi: 10.18632/oncotarget.17937

Table 3. Parameters of CastPCR detecting EGFR and BRAF mutations in cfDNA#.

Parameters EGFR BRAF
Sensitivity 56.4%(31/55) 28.6% (2/7)
Specificity 94.2%(49/52) 93.0% (93/100)
Concordance 74.8%(80/107) 88.8% (95/107)
PPV 91.2% (31/34) 22.2% (2/9)
NPV 67.1% (49/73) 94.9% (93/98)

# Mutation results of FFPE was set the gold standard

PPV: Positive Predictive Value; NPV: Negative Predictive Value.