Table 3. Parameters of CastPCR detecting EGFR and BRAF mutations in cfDNA#.
Parameters | EGFR | BRAF |
---|---|---|
Sensitivity | 56.4%(31/55) | 28.6% (2/7) |
Specificity | 94.2%(49/52) | 93.0% (93/100) |
Concordance | 74.8%(80/107) | 88.8% (95/107) |
PPV | 91.2% (31/34) | 22.2% (2/9) |
NPV | 67.1% (49/73) | 94.9% (93/98) |
# Mutation results of FFPE was set the gold standard
PPV: Positive Predictive Value; NPV: Negative Predictive Value.