Figure 2. EC0347 and EC1820 disrupt the cellular microtubule network upon 4h drug exposure.

2008/WT cells where transfected with a G-β-myc expression vector and subjected to a 4h pulse treatment with 20nM EC0347 or EC1820. Immunofluorescence microscopy was performed, as detailed under Materials and Methods, using drug-free control cells (A), EC0347 (B), and EC1820 (C) treated cells to evaluate the status of the microtubule network (red fluorescence), and G-β-myc (green fluorescence) as a plasma membrane marker.