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. 2017 Jun 7;8(30):50015–50022. doi: 10.18632/oncotarget.18388

Figure 3. CA125 increases cell migration via the Wnt signaling pathway.

Figure 3

Transwell migration assays were performed to assess the effect the DKK-1 (200 ng/ml), a Wnt pathway inhibitor, on migration of A2780 (A, B) and OVCAR-3 (C, D) cells exposed to 0.2 μg/ml or 0.4 μg/ml CA125 for 48 h. The cell number was counted by counting black spot in the high magnification image (red arrow pointed). (E) Western blot analysis of CA125 levels in A2780 and 0VCAR3 cells. The data were normally distributed, and they were analyzed using one-way ANOVA (n=3). *P < 0.05; **P < 0.01.