Figure 1. MiRNAs in PCa pathogenesis.
Schematic representation of prostate cancer pathogenesis and miRNAs involved in this process. Cell cycle block and apoptosis resistance lead to cancer; afterwards, prostate cancer cells are subjected to epithelial mesenchymal transition (EMT), which confers increased migratory capacity and invasiveness to generate metastases. Over-expressed miRNAs are highlighted in red, down-expressed miRNAs are highlighted in green.