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. 2017 May 24;8(30):50305–50313. doi: 10.18632/oncotarget.18148

Table 1. Mutation analysis of glioblastoma multiforme patient tumor.

Gene Variation type Nucleotide variation Amino acid variations Sequencing depth Mutation frequency
EGFR point mutation c.C866T p.A289V 7941 95%
EGFR insertion mutation c.2318_2319insACC p.P773delinsPP 7932 9.50%
FLNA point mutation c.G3718A p.V1240M 250 20.80%

EGFR gene amplification 14 times