Table 1. Mutation analysis of glioblastoma multiforme patient tumor.
Gene | Variation type | Nucleotide variation | Amino acid variations | Sequencing depth | Mutation frequency |
---|---|---|---|---|---|
EGFR | point mutation | c.C866T | p.A289V | 7941 | 95% |
EGFR | insertion mutation | c.2318_2319insACC | p.P773delinsPP | 7932 | 9.50% |
FLNA | point mutation | c.G3718A | p.V1240M | 250 | 20.80% |
EGFR gene amplification 14 times