Table 2. Progression of the patient's illness and the therapeutic regimen.

Time	Patient history and treatment regimen
Feb, 2015	Headache, vomiting, and mild left hemiparesis. The patient was diagnosed with glioblastoma and underwent gross total resection.
March/April, 2015	Standard radiation and concomitant temozolomide chemotherapy.
May, 2015-Sept, 2015	Adjuvant temozolomide 5 cycles (150mg/day in first cycle, 200mg/day in other cycle)
Sept, 2015	The relapse of the GBM
Oct, 2015	Next generation sequencing demonstrates EGFR mutation
Oct, 2015	Perform a PET/CT by EGFR antibody-18-FDG shows non-uniform EGFR positive reaction
Nov, 2015	Oral administration of erlotinib 150 mg/day
Nov, 2015-Feb, 2016	SD (less edema and reduced compression of the lateral ventricles)
March, 2016	Recurrence of GBM
May,2016	Patient death

GBM: Glioblastoma multiforme SD: Stable Disease