Table 2.
Fingolimod (N = 271) |
Dimethyl fumarate (N = 342) |
||||
---|---|---|---|---|---|
N or mean | % or SD | N or mean | % or SD | p value | |
Discontinued drug ≤24 months | 93 | 34.3% | 161 | 47.1% | 0.001 |
Disease activitya | 27 | 10.0% | 38 | 11.1% | 0.647 |
Adverse events | 46 | 17.0% | 82 | 24.0% | 0.034 |
Insurance | 2 | 0.7% | 4 | 1.2% | 0.699 |
Lost to follow-up | 15 | 5.5% | 27 | 7.9% | 0.251 |
Other | 3 | 1.1% | 10 | 2.9% | 0.161 |
Mean time to discontinuation (months)b | 10.3 | 7.1 | 10.0 | 7.2 | 0.539 |
Includes discontinuation of drug because of clinical relapse, magnetic resonance imaging activity or disease progression.
For those who discontinue.