Table 3.
Fingolimod (N = 271) |
Dimethyl fumarate (N = 342) |
||||
---|---|---|---|---|---|
N or mean | % or SD | N or mean | % or SD | p value | |
Patients with a relapse during first two years of study drug | 24 | 8.9% | 44 | 12.9% | 0.116 |
MRI available while on drug in first two years | 214 | 79.0% | 260 | 76.0% | 0.387 |
Mean number of available MRIs | 1.64 | 0.69 | 1.63 | 0.68 | 0.895 |
Patients with contrast enhancement | 28 | 13.1% | 26 | 10.0% | 0.293 |
Patients with new T2 lesions | 75 | 35.1% | 82 | 31.5% | 0.419 |
Composite efficacy measurea | 94 | 34.7% | 115 | 33.6% | 0.783 |
Patients who had a clinical relapse, contrast enhancement or a new T2 lesion on follow-up MRI.
MRI: magnetic resonance imaging.