Stage	State	Stage Onset	Hindlimb Presentation
0	Pre-symptomatic	< P100	No notable differences compared to wildtypes.
1	Disease onset	~ P100	Hindlimb collapse when mouse is suspended from tail.
2	Paresis	~ P120	Full or partial hindlimb collapse with appearance of tremor.
3	Paralysis onset	~ P140	Difficulty walking, toe curling and/or foot dragging.
4	Advanced paralysis	~ P150	Minimal joint movement, hindlimb not being used for forward motion.
5	Endstage	~ P160	Mouse unable to right itself from side within 30 seconds.