Table 1.

Changes in graph metrics in PDs compared with HVs

Node strength	Clustering	Local efficiency	Betweenness
CON
L dAI↓	R IFG pars Tri↓ˆ	L post MTG/STG↓	L dAI↓
R ITG↓		L TPJ↓	L TPJ↓ˆ
L post MTG/STG↓		R ITG↓*	R MI↓ˆ
L TPJ↓		R STG↓*
FPN
–	–	L IPS↓ˆ	R OFG↓ˆ
SMN
R preCG1↓	R preCG1↓	R preCG1↓	L MI↑
L STG1↓	L preCG1↓	L preCG1↓	L preCG2↑
RPI↓ˆ	L preCG2↓*	R preCG3↓*
	L STG2↓	L STG1↓ˆ
	R postCG↓*	L STG3↓ˆ
	L postCG↓ˆ
	R preCG2↓ˆ

The up and down arrows display the significant changes in graph metrics in PD relative to the HV group. Note that the node labels in this study were determined based on the MNI probabilistic maps in AFNI

CON cingulo-opercular network, FPN frontoparietal network, SMN sensorimotor network, L left, R right, post posterior, dAI dorsal anterior insula, ITG inferior temporal gyrus, MTG middle temporal gyrus, STG superior temporal gyrus, TPJ temporoparietal junction, IFG inferior frontal gyrus, Tri triangularis, preCG precentral gyrus, postCG postcentral gyrus, OFG orbitofrontal gyrus, IPS intraparietal sulcus, MI midinsula, PI posterior insula

^*p ≤ 0.05 at six out of seven and

^ˆp ≤ 0.05 at five out of seven correlation thresholds (0.1 ≤ r ≤ 0.4 in increments of 0.05). For all other nodes, p ≤ 0.05 across seven correlation thresholds