Fig. S3.

Peptidergic and nonpeptidergic neurons are transduced with similar efficiency by lentiviral injections. (A) A section of the L4 DRG stained for IB4 and its corresponding GFP expression (B) identifies lentiviral transduction of nonpeptidergic neurons (arrows). (C) Staining for CGRP in an L4 DRG section and corresponding GFP staining (D) identifies peptidergic neurons transduced by retrogradely transported lentivirus (arrows). (E) Comparison of percentage of neurons transduced in L4–L5 DRG that are nonpeptidergic vs. peptidergic reveals no difference (i.e., subpopulation-specific bias) (n = 5 animals). (Scale bar, 50 µm.)