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. 2017 Jul 31;114(33):E6952–E6961. doi: 10.1073/pnas.1618210114

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Fig. S4. — Effect of DRG gene modulation on central projections to the spinal cord. (A and B) MeCP2 knockdown in DRG of WT rats. Analysis of lumbar spinal cord from rats in which DRG neurons were transduced for MeCP2 expression revealed no difference in gray matter area occupied by nonpeptidergic IB4⁺ projections (A) or CGRP-ir projections (B). Multigene knockdown in DRG of MeCP2 KO rats. (C and D) Analysis of lumbar spinal cord from KO rats in which footpad-projecting DRG neurons underwent knockdown of eight key cytoskeleton-related genes showed no changes in IB4⁺ (C) or CGRP-ir (D) central projections.