. 2017 Jul 31;114(33):8841–8846. doi: 10.1073/pnas.1704277114

Table 1.

Epistasis analysis of the supersized LD phenotype

Genotype and treatment	% SLD⁺	n
cyp-37A1(ssd9)	100	109
cyp-37A1(ssd2)	100	100
cyp-37A1(ok673)	100	97
emb-8(ssd89)	98.8	83
cyp-37A1(ssd9); daf-12(ssd155)	0	62
cyp-37A1(ssd9); daf-12(m583)	1.0	97
emb-8(ssd89); daf-12(m583)	0	102
cyp-37A1(ssd9) + WT LE(1X)	49.2	61
cyp-37A1(ssd9) + WT LE(1X)-Del	100	73
cyp-37A1(ssd9) + cyp-37A1(ssd9) LE(1X)	94.7	95
cyp-37A1(ssd9) + cyp-37A1(ssd9) LE(1X)-Del	100	69
cyp-37A1(ssd9)+ DA^Δ7(0.02 µM)	79.3	58
cyp-37A1(ssd9)+ DA^Δ7(0.2 µM)	87.7	57
cyp-37A1(ssd9)+ DA^Δ7(2 µM)	55.9	102
cyp-37A1(ssd9)+ DA^Δ7(0.02 µM)^*	98.4	63
cyp-37A1(ssd9)+ DA^Δ7(0.2 µM)^*	95.5	66
cyp-37A1(ssd9)+ DA^Δ7(2 µM)^*	90.2	61
daf-9(e1406)^†	87	54
daf-9(e1406)+ DA^Δ7(0.2 µM)^†	3.4	58
daf-9(e1406)+ DA^Δ7(2 µM)^†	0	58
daf-36(k114)^†	21.4	56
daf-36(k114) + DA^Δ7(0.2 µM)^†	14	57
daf-36(k114) + DA^Δ7(2 µM)^†	0	56
daf-12(rh274)	100	54
din-1(dh149); daf-12(rh274)	0	81
din-1(dh149); daf-9(e1406)	0	81
din-1(dh149); daf-36(k114)	0	87
din-1(dh127) cyp-37A1(ssd9)	94.2	104
din-1(dh127) cyp-37A1(ssd9); daf-9(e1406)	11.1	45
din-1(dh149) cyp-37A1(ssd9); daf-36(k114)	98.5	66

All data are of L4 stage animals shifted to 30 °C for 4 h unless otherwise indicated. % SLD⁺, percentage of animals with supersized LDs. LE(1X), total lipid extract equivalent to 6 mg total protein. LE-Del, total lipid extract delipidated.

Scored at L3 stage.

^{^†}

Scored at 20 °C.