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IFNG is a master regulator of cytokine-driven odontoblastic differentiation. DPSCs were coinfected with IFNG lentivirus and a lentivirus containing one of the 16 differentiation-inducing cytokines (Top). IFNG inhibited an increase in ALP activity induced by any of those differentiation-inducing cytokines. IFNG also suppressed the increase of ARS staining induced by cytokines (Bottom). Data are shown as mean + SD (n = 6). **P < 0.01, ***P < 0.001.
