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IFNG checkpoint is controlled as an autocrine system. DPSCs were treated with lentiviruses containing control vector or OSM. (A) ARS staining shows odontoblastic differentiation over the time course of 12 d with or without OSM. (B and C) RNA samples were collected on days 0, 3, 6, 9, and 12 to compare mRNA levels of IFNG (B) and IFNG receptor (C) over time. Data are shown as mean + SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, ##P < 0.01, ###P < 0.001.
