Fig. S6.

IFNG inhibits OSM-induced Collagen I production in human lung fibroblasts (HLFs). (A) HLFs were infected with IFNG and OSM lentiviruses alone or in combination. Collagen I mRNA level was analyzed by real-time PCR 3 d after infection. Data are shown as mean + SD (n = 3). (B and C) FACS analysis shows that treatment with DMSO or recombinant IFNG for 10 or 60 min decreased gp130 antibody staining on the cell surface of HLFs. Pretreatment with a p38 inhibitor for 1 h prevented those changes. ***P < 0.001.