Table 2.
Group | SF1 | SF3 |
L-ON | ▲ | ▲ |
L-OFF | ▬ | ▲ |
All | ▲ | ▲ |
ON T | ▬ | ▲ |
ON S | ▬ | ▬ |
ON-OFF | ▬ | ▬ |
OFF T | ▬ | ▲ |
Center subfilter (SF1) is accelerated in IOP mice primarily in L-ON RGCs, whereas center subfilter 3 (SF3) is accelerated in both L-ON and L-OFF RGCs. The change in center subfilter 3 is mediated by ON and OFF Trans RGCs. Both ON Sust and ON-OFF RGCs had nonsignificant acceleration. Arrowheads indicate significant increase (Table S2).