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. Author manuscript; available in PMC: 2017 Aug 21.
Published in final edited form as: Clin Pharmacokinet. 2011 Jan;50(1):1–24. doi: 10.2165/11536640-000000000-00000

Fig. 1.

Fig. 1

Outline of mycophenolate mofetil (MMF) absorption and dissolution in the body by known or proposed drug-metabolizing enzymes and transporters. ABCB1 (formally, MDR1 = multidrug resistance 1)=adenosine triphosphate-binding cassette, sub-family B, member 1; ABCC2 (formally, MRP2=multidrug resistance-associated protein 2) = adenosine triphosphate-binding cassette, sub-family C, member 2; AcMPAG = MPA acyl-glucuronide; CES =carboxyesterases; IMPDH=inosine monophosphate dehydrogenase; MPA=mycophenolic acid; MPAG=7-O-MPA-β-glucuronide; SLCO (formally, OATP=organic anion-transporting polypeptide)=solute carrier organic anion transporter family; UGT =uridine diphosphate glucuronosyltransferase.