Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Final CDRs for JAA-F11 heavy and light chain variable regions. Final CDRs as determined by Kabat (sequence) in red, Chothia (structure) in blue boxes, amino acids 5 Å from binding site (pink) or 6 Å from binding site (yellow). Black underlined = CDRs selected for humanization. In addition cysteine at position L23 and L88 (green) were maintained. (A) Heavy chain. (B) Light chain. Numbering is according to Kabat. Letters a, b, c, refers to insertions.
