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Example RFU Graph Showing High Degree of Specificity of These Antibodies.
| Chart ID | Saccharides of 601 Tested With ≥15% Binding to Any of the Antibodies | H3L3 Average RFU | H2aL2a Ave RFU | Chimeric Ave RFU |
|---|---|---|---|---|
| 139 | Galb1–3GalNAcα-Sp8 | 13,343 | 21,619 | 13,860 |
| 137 | Neu5Acβ2–6(Galβ1–3)GalNAcα-Sp8 | 7391 (55%) | 25,576 (118%) | 5390 (38%) |
| 135 | Neu5Acα2–6(Galβ1–3)GalNAcα-Sp8 | 1016 (8%) | 6921 (32%) | 3240 (23%) |
Saccharides shown if RFU ≥15% of Galβ1–3GalNAcα-Sp8 value for any construct.
