Table I.
Size and estimated diameter of molecules of relevance to pyroptosis
| Exists as | Molecular weight (Da) | Max Diameter | |
|---|---|---|---|
| H20 | Small molecule | 18 | 0.275 nm |
| Na+ | Ion | 23 | 0.277 nm |
| Glycine | Small molecule | 75 | 0.97 nm |
| Propidium | Small molecule | 562 | 1.38 nm |
| IL-1β | Mature monomer | 17,376 | 4.5 nm |
| IL-18 | Mature monomer | 18,239 | 5.0 nm |
| GFP | Monomer | 26,900 | 5.4 nm |
| tdRFP | Tandem dimer* | 56,600 | Dimer of 5.6 nm |
| LDH | Tetramer* | 146,800 | 9.6 nm |
*
Molecular weight and diameter of the tandem dimer and tetramer are shown. Maximum diameters were measured using MacPyMOL.