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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Pharmacol Ther. 2017 Mar 6;177:96–107. doi: 10.1016/j.pharmthera.2017.03.001

Table 2.

List of inhibitors of deubiquitinase and their biological function.

DUBs Inhibitor Biological function
USP7 P022077, P5091,Cpd 14,P22077, HBX 41,108, HBX-19,818 and HBX-28,258 Cell fate determinants
USP8 HBX 90,397 and Ethyloxyimino-9H-indeno [1,2-b]pyrazine-2,3-dicarbonitrile Invasive growth
USP9X, USP5, USP14, and UCH37 WP1130 Apoptosis
USP14, UCH37 b-AP15 and VLX1570 Tumor cell invasion
USP1 Pimozide Cell fate determinants
UCHL1 LDN91946, LDN-57444, Δ12-PGJ2 and 15Δ-PGJ2 EMT
UCHL3 LS1, Δ12-PGJ2 and 15Δ-PGJ2 EMT
USP30 15-oxospiramilactone Apoptosis