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. Author manuscript; available in PMC: 2017 Aug 22.
Published in final edited form as: J Invest Dermatol. 2016 Nov 1;137(4):819–827. doi: 10.1016/j.jid.2016.10.028

Figure 1. Detection of MCPyV DNA and oncoprotein in MCC tumors.

Figure 1

Schematic diagram of the MCPyV small and large Tantigens. Numbers correspond to the nucleotide position in the MCPyV genome. The LT4 primer set targets a 60-base pair segment of the persistently expressed portion of the truncated large T antigen. The asterisk indicates the TaqMan probe location (see Materials and Methods for details). The colored brackets in the lower portion of the figure show amino acid positions of antigens used to generate the large T antibodies: CM2B4 (blue) and Ab3 (red). a. a., amino acid; MCC, Merkel cell carcinoma; MCPyV, Merkel cell polyomavirus.