Table 1.

Individual performance of the three assays (qPCR, CM2B4, and Ab3) in classifying intratumoral MCPyV in Merkel cell carcinoma compared with the multimodal approach¹

	Virus-Positive, n*	Virus-Negative, n*	Total, n	Assay Sensitivity	Assay Specificity
qPCR-pos	189	10	199
qPCR-neg	40	43	83
Total	229	53	282	0.825	0.811
CM2B4-pos	202	3	205
CM2B4-neg	27	50	77
Total	229	53	282	0.882	0.943
Ab3-pos	225	29	254
Ab3-neg	4	24	28
Total	229	53	282	0.983	0.453

Abbreviations: neg, negative; pos, positive.

¹Tumor viral status as determined by the multimodal approach (at least two of the three assay results in agreement).