Table 2.
Baseline characteristics of MCC patients, by tumor MCPyV status, Fred Hutchinson Cancer Research Center, 2004–2012
| Characteristics | Virus-Negative n = 53 | Virus-Positive n = 229 | ||
|---|---|---|---|---|
| Patient characteristics | Median | SD | Median | SD |
| Median age, years | 71 | 11.2 | 71 | 12.6 |
| n | % | n | % | |
| Sex | ||||
| Female | 18 | 34.0 | 87 | 38.0 |
| Male | 35 | 66.0 | 142 | 62.0 |
| Race | ||||
| White | 51 | 98.1 | 221 | 96.9 |
| Other | 1 | 1.9 | 7 | 3.1 |
| Immunosuppression | ||||
| Absent | 51 | 96.2 | 211 | 92.1 |
| Present | 2 | 3.8 | 18 | 7.9 |
| Tumor characteristics | Median | SD | Median | SD |
| Primary tumor size, cm | 1.1 | 1.7 | 1.9 | 1.7 |
| n | % | n | % | |
| Site of primary tumor | ||||
| Head and neck | 22 | 41.5 | 74 | 32.3 |
| Trunk | 6 | 11.3 | 10 | 4.4 |
| Buttock/genitalia | 2 | 3.7 | 18 | 7.9 |
| Extremity | 10 | 18.8 | 100 | 43.7 |
| Unknown primary | 13 | 24.5 | 27 | 11.8 |
| Stage at Diagnosis | ||||
| Local | 14 | 33.3 | 93 | 51.7 |
| I | 10 | 23.8 | 65 | 36.1 |
| II | 4 | 9.5 | 28 | 15.6 |
| Advanced | 28 | 66.7 | 87 | 48.3 |
| III | 20 | 47.6 | 61 | 33.9 |
| IV | 8 | 19.1 | 26 | 14.4 |
| Treatment | ||||
| Surgical excision | ||||
| Yes | 29 | 74.4 | 187 | 93.0 |
| No | 10 | 25.6 | 14 | 7.0 |
| Radiation | ||||
| Yes | 29 | 61.7 | 138 | 64.2 |
| No | 18 | 38.3 | 77 | 35.8 |
| Chemotherapy | ||||
| Yes | 10 | 19.2 | 30 | 13.3 |
| No | 42 | 80.8 | 195 | 86.7 |
Abbreviations: MCC, Merkel cell carcinoma; MCPyV, Merkel cell polyomavirus; SD, standard deviation.