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. Author manuscript; available in PMC: 2017 Aug 22.
Published in final edited form as: Med Biol Eng Comput. 2008 Jun 4;46(10):1039–1049. doi: 10.1007/s11517-008-0354-7

Table 2.

Doxorubicin coverage of simulated and experimental tissues.

Model Experimental
Day 4 Day 8 Day 4 Day 8
Ablated liver model (Condition A)
Area of ablated liver (mm3) 254 254 155 186
Ablated liver over [DOX*] (%) 98.3% 98.8% 98.0% 98.3%
[DOX] in ablated liver (µg/g)a 205 [117–430] 295 [192–398] 590 [166–1311] 1008 [361–1796]
Ablated tumor model (Condition B)
Area of ablated tumor (mm3) 254 254 343 418
Area of non-ablated tumor (mm3) 60 60 195 90
Non-ablated tumor over [DOX*] (%) 100% 61% 87% 65%
[DOX] in non-ablated tumor (µg/g)a 140 [78–232] 20 [8–56] 79 [30–173] 26 [7–87]
a

Values shown are the median concentration. Brackets contain the 25th and 75th percentiles.