Table 3.
Variable ** | PCOS TSH <4.2 μUI/ml | PCOS-with-SCH TSH ≥4.2 μUI/ml | Control TSH <4.2 μUI/ml | |||
---|---|---|---|---|---|---|
n | Mean±SD | n | Mean±SD | n | Mean±SD | |
TSH (mmol/l) | 417 | 1.99±0.86 | 30 | 7.83±7.48 | 195 | 1.96±0.81a,b |
FT4 (pmol/l) | 402 | 14.31±2.39 | 27 | 12.68±2.91 | 191 | 13.93±2.08 a,c |
PRL (nmol/l) | 404 | 558.02±293.24 | 27 | 586.80±237.98 | 182 | 627.69±287.7d |
E2 (pmol/l) | 301 | 185.57±66.67 | 18 | 173.08±58.46 | 157 | 163.93±63.48 e |
Tt (nmol/l) | 397 | 2.03±0.92 | 26 | 1.69±0.63 | 155 | 1.03±0.48 b,e |
FT (nmol/l) | 370 | 0.05±0.03 | 26 | 0.04±0.04 | 151 | 0.01±0.009 b,e |
SHBG (nmol/l) | 363 | 35.58±19.88 | 23 | 37.73±21.17 | 145 | 64.84±32.71b,e |
FAI (%) | 352 | 7.46±5.37 | 21 | 5.97±3.70 | 139 | 2.05±1.85 b,e |
FSH (mUI/ml) | 397 | 5.77±1.77 | 25 | 6.43±1.61 | 178 | 7.18±2.14e |
LH (mUI/ml) | 394 | 10.06±5.80 | 27 | 8.39±3.94 | 175 | 5.08±2.59 b,e |
17-OHP4 (nmol/l) | 390 | 0.038±0.021 | 27 | 0.033±0.014 | 145 | 0.028±0.030 e |
DHEAS (nmol/l) | 383 | 4.92±2.37 | 24 | 4.42±1.60 | 153 | 3.91±1.96 e |
Androstenedione (nmol/l) | 378 | 0.110±0.111 | 26 | 0.12±0.18 | 144 | 0.075±0.215d |
One way analysis of variance followed by post hoc Tukey test;
PCOS=patients with PCOS and TSH<4.2 μUI/ml.
PCOS-with-SCH=patients with PCOS and TSH>4.2 μUI/ml. Control=normal women with TSH <4.2 μUI/ml
p<0.001 PCOS vs. PCOS-with-SCH;
p<0.001 PCOS-with-SCH vs. control;
p=0.041 PCOS-with-SCH vs. control;
p=0.007 PCOS vs. Control;
p<0.001 PCOS vs. control