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. 2017 Jul 7;49(7):e352. doi: 10.1038/emm.2017.89

Table 2. Bcl3 mRNA expression in kidney disease according to transcriptomics databases.

Condition Comparator Species Fold-change P-value Database Reference
Brain death tubulointerstitium Cadaveric vs Living donor Human 1.45 0.057 Nephromine 53
Brain death tubulointerstitium Cadaveric vs Living donor Human 1.69 0.001 Nephromine 54
Hypertension tubulointerstitium Hypertension vs Living donor Human 1.12 0.009 Nephromine 54
Diabetic nephropathy tubulointerstitium Diabetes vs minimal change disease Human 1.22 0.04 Nephromine 53
IgA nephropathy tubulointerstitium Nephrotic vs Sub-nephrotic proteinuria Human 1.18 0.039 Nephromine 55
Glomerulonephritis Tubulointerstitium Rapidly progressive glomerulonephritis vs Healthy living donor Human 1.18 0.043 Nephromine 54
Thin basement membrane disease Tubulointerstitium Thin basement membrane disease vs Healthy living donor Human 1.21 0.009 Nephromine 54
Minimal change glomeruli Minimal change vs Normal control Human 1.58 0.001 Nephromine 56
Membranous glomerulonephritis Glomeruli Membranous glomerulonephritis vs Healthy living donor Human 1.19 0.008 Nephromine 54
Thin basement membrane disease Glomeruli Thin basement membrane disease vs Healthy living donor Human 1.15 0.006 Nephromine 54
Diabetic nephropathy Glomeruli Diabetic nephropathy vs Healthy living donor Human 1.2 0.027 Nephromine 54
Lupus nephritis Glomeruli Lupus nephritis vs Healthy living donor Human 1.09 0.042 Nephromine 54
Kidney graft Nephrotoxicity, chronic allograft nephropathy vs Normal kidney Human 1.34 0.044 Nephromine 57
Kidney graft, living donor Kidney dysfunction vs Normal kidney Human 1.46 0.0004 Nephromine 58
Kidney graft, cadaveric donor Acute rejection vs No rejection Human 1.49 0.0004 Nephromine 58
Lupus nephritis Glomeruli MRLLpr vs Control Mouse 12.1   KUPKB 59
Lupus nephritis Proteinuria vs No proteinuria Mouse 2.46 0.000002 Nephromine 60
Aquaporin-11 deficiency effect on the kidney AQP11 null vs Control Mouse 3.15 0.001 GEO Profiles 61
Nephronophthisis GLIS2 mutant vs WT Mouse 1.58 0.002 GEO Profiles 62
Dent disease CLCN5 null vs WT Mouse 1.46 0.048 GEO Profiles 63
Hypertension Hypertension vs Normotension Mouse 1.13 0.024 GEO Profiles 64
Hypertension Hypotension vs Normotension Mouse 1.31 0.014 GEO Profiles 64
Methylmalonic acidemia-associated renal disease MMA mutant vs WT Mouse 1.28 0.005 GEO Profiles 65
Methylmalonic acidemia-associated renal disease MMA heterozygote vs WT Mouse 1.12 0.027 GEO Profiles 65
Cephaloridine effect on the kidney Cephaloridine vs Control Rat 2.5 0.009 GEO Profiles 66
Salt-sensitive hypertension Dahl vs Control Rat 2.12 0.007 GEO Profiles 67
Polycystic kidney disease Polycystic kidney disease vs Control Rat 1.41 0.0002 KUPKB 68

(GEO profiles (http://www.ncbi.nlm.nih.gov/geoprofiles/?term=bcl3+kidney), Kidney & Urinary Pathway Knowledge Base (kupkb at http://www.kupkb.org/) and nephromine (http://www.nephromine.org/)).