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. 2017 Apr 14;102(7):1204–1214. doi: 10.3324/haematol.2016.163022

Figure 2.

Figure 2.

DNA methylation levels at UNCX canyon in our acute myeloid leukemia (AML) patient cohort and TCGA samples. Mean values of DNA methylation ratios (MRs) of MassARRAY amplicons obtained for each of the 20 amplicons tested at both 5′ (A) and 3′ (B) UNCX canyon borders; P-values are reported above each amplicon showing a significant increase in the average MR in UNCX+ versus UNCX− patients. (C) Box and Whisker plot showing DNA methylation β values at the UNCX canyon in UNCX-TCGA-positive (n=55, median 0.3471, interquartile range 0.2898–0.3981) and UNCX-TCGA-negative (n=56, median 0.2771, interquartile range 0.2273–0.3348) patients. Significant differences were identified using the Mann-Whitney U-test (P<0.0001).