Table 2.
Comparison of cell density and cell area of corneal layers between keratoconus and healthy eyes
| Parameters | Keratoconusa (n=47) | Healthy eyesa (n=32) | Mean difference (95% CI) | t-statistic (df) | P-value* |
|---|---|---|---|---|---|
|
|
|
||||
| Mean (SD) | Mean (SD) | ||||
| ASKD (cells/mm2) | 885.08 (47.34) | 1095.71 (101.85) | 210.63 (176.64, 244.53) | 12.37 (77) | 0. |
| ASKA (μm2) | 1132.96 (59.89) | 925.79 (84.89) | −207.16 (−239.57, −174.75) | −12.72 (77) | 0. |
| PSKD (cells/mm2) | 705.78 (47.65) | 808.15 (88.85) | 102.37 (71.64, 133.11) | 6.63 (77) | 0. |
| PSKA (μm2) | 1423.55 (98.99) | 1250.90 (138.34) | −172.65 (−225.79, −119.50) | −6.46 (77) | 0. |
| ECD (cells/mm2) | 2860.04 (215.28) | 2946.71 (194.52) | 86.67 (−7.87, 181.22) | 1.82 (77) | 072 |
| ECA (μm2) | 348.51 (22.75) | 332.30 (42.19) | −16.20 (−30.83, −1.59) | −2.20 (77) | 030 |
|
| |||||
| (n=13) | (n=21) | ||||
|
| |||||
| SBNFD (cells/mm2) | 13.3 (7.3) | 19.1 (5. 2) | 5.8 (11.23, 21.32) | 1.31 (32) | 0. |
| SBNFL (mm/mm2) | 11.2 (4.1) | 18.5 (3.5) | 7.3 (9.37, 16.21) | 1.27 (32) | 0. |
a
Mean(standard deviation).
*
Independent t-test.
n: Number of patients with keratoconus. t: t-statistics. df: Degree of freedom. CI: Confidence intervals, ASKD: Anterior stromal keratocyte density. ASKA: Anterior stromal keratocyte area. PSKD: Posterior stromal keratocyte density. PSKA: Posterior stromal keratocyte area. ECD: Endothelial cell density. ECA: Endothelial cell area. SBNFD: Sub-nasal nerve fibers density. SBNFL: Sub-basal nerve fibers length.