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. 2017 Jul 21;7(12):2982–2995. doi: 10.7150/thno.19374

Figure 12.

Figure 12

Serum stability of the siRNA-aptamer chimera containing 2'-OMe modification. 2'-OMe modified sense strand of the PCPB2 siRNA was annealed with the antisense strand and then form the chimera with the DNA aptamer-20. The siRNA-aptamer chimera was incubated in rat serum for various time intervals and subjected for electrophoresis with 20% native PAGE.