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Biodistribution of the PCBP2 siRNA-aptamer chimera in rats with CCl4-induced liver fibrosis. The antisense strand of the PCBP2 siRNA was labeled with Alexa-647. Two nmols of the siRNA-aptamer chimera were injected into the rats via the tail vein. After 1h, the rats were sacrificed, and major organs were harvested for imaging analysis using a BRUKER In-Vivo MS FX PRO system. Data are presented as mean ± SD (n=3).
