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Cellular imaging and in vitro cytotoxicity. a) In vitro cellular imaging and localization of free DOX and different NPs, monitored in A549 cell; b) In vitro combination therapeutic effect of free DOX, the PEG-Si/C NPs, the PEG-Si/C-DOX NPs with or without 808 nm laser irradiation at a power density of 0.5 W/cm2 for 5 min; c) In vitro cytotoxicity of the PMHC18-PEG.
