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. 2016 Apr 12;2(2):161–177. doi: 10.1007/s40674-016-0045-8

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Mechanism of the onset of antineutrophil cytoplasm antibody (ANCA)-associated vasculitis. LAMP-2 lysome-associated membrane protein-2, MPO myeloperoxidase, NETs neutrophil extracellular traps, PR3 proteinase 3, ROS reactive oxygen species. Reprinted from [11], by permission of Nature Publishing Group and Macmillan Publishers Ltd.