Table 2.

Effect of TVL on serum SOD activity, TBARS, NO, urea and creatinine levels in non-diabetic rats treated with distilled water, non-diabetic control (NDC); and TVL 60 mg/kg.b.w.(ND +TVL) as well as diabetic rats treated with distilled water, diabetic control (DC); TVL60mg/kg.b.w.(D+TVL) and metformin 250mg/kg.b.w (D+metformin). All data are expressed as mean±SEM for 6 animals per group.

Parameters	Experimental groups
	NDC	ND+ TVL	DC	D+TVL	D+Metformin
SOD (% inhibition)	82.37±5.43	77.16±4.84	52.90±5.69**$	82.07±1.69#	80.48±1.68#
TBARS (nmol)	219.60±0.015	205.10±0.009	314.10± 0.008***###	211.50±0.008#	212.60±0.015##
NO (uM)	27.35±1.85	28.39±0.83	18.86±1.42**$	28.61±1.72#	26.80±2.97
Serum urea (mmol/L)	4.94±0.21	5.33±0.26	26.70±2.13***$$$	11.67±1.65*###	18.57±2.43***$$$#
Serum creatinine (mmol/L)	37.00±0.63	37.33±0.88	34.33±0.67	32.33±5.18	34.67±1.20

^*Significantly different from non-diabetic control, p<0.05.

^**Significantly different from non-diabetic control, p<0.01

^***Significantly different from non-diabetic control, p<0.001.

^$Significantly different from non-diabetic+TVL, p<0.05.

^$$$Significantly different from non-diabetic+TVL, p<0.001.

^#Significantly different from diabetic control, p<0.05

^##Significantly different from diabetic control, p<0.01.

^###Significantly different from diabetic control, p<0.001.