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. 2017 Apr 19;4(8):1600493. doi: 10.1002/advs.201600493

Figure 3.

Figure 3

Impairment of basic synaptic transmission and long‐term plasticity (LTP) in the hippocampal CA1 areas after juvenile BPA exposure. A) Input/output (I/O) curves showed the fEPSP slopes as a function of stimulus current intensities in control and BPA‐exposed groups. I/O was significantly depressed in BPA‐exposed rats compared with that of the control value (n = 10 rats per group, **p < 0.01). B) The magnitude of LTP was assessed by the fEPSP slope (percentage of baseline) in every 5 min within 60 min after high frequency tetanic stimulation (HFS) (n = 10 rats per group, ***p < 0.001). C) Histogram showing a significant decrease of LTP magnitude in 60 min of juvenile BPA‐exposed rats (n = 10 rats per group, **p < 0.01). Arrow indicates of HFS application.