Figure 3.
Incidence of IAA only, GADA only, and IA-2A only as first-appearing IA and multiple IA at seroconversion by HLA genotype DR3/4 (A), DR4/4 (B), DR4/8 (C), and DR3/3 (D). A: IAA only appeared in 125 of 3,317 children, GADA only in 111 of 3,317, IA-2A only in 3 of 3,317, and multiple IA in 59 of 3,317. B: IAA only appeared in 44 of 1,661 children, GADA only in 34 of 1,661, IA-2A only in 3 of 1,661, and multiple IA in 22 of 1,661. C: IAA only appeared in 53 of 1,470 children, GADA only in 24 of 1,470, IA-2A only in 2 of 1,470, and multiple IA in 9 of 1,470. D: IAA only appeared in 17 of 1,782 children, GADA only in 54 of 1,782, IA-2A only in 1 of 1,782, and multiple IA in 4 of 1,782.