Table 3.
Baseline factors associated with persistent radiographic findings suggestive of nontuberculous mycobacteria in patients with radiographic evaluations at least 2 years (n = 93) or at least 5 years (n = 65) after initial isolation
| Baseline Patient Characteristics | Patients with Scans (n) | Findings at ≥2 Yr | Nodules, Cavitation, or Infiltrate vs. No Findings at ≥2 Yr |
Patients with Scans (n) | Findings at ≥5 Yr | Nodules, Cavitation, or Infiltrate vs. No Findings at ≥5 Yr |
||
|---|---|---|---|---|---|---|---|---|
| OR | AOR | OR | AOR | |||||
| Overall | 93 | 65 | ||||||
| Met case criteria* | 61 | 54 (88.5) | 3.5 (1.2–10.4) | 2.0 (0.6–6.8) | 44 | 36 (81.8) | 1.8 (0.5–6.1) | 1.1 (0.2–5.2) |
| Did not meet case criteria | 32 | 22 (68.8) | 21 | 15 (71.4) | ||||
| Treatment initiated | 45 | 42 (93.3) | 5.8 (1.5–21.7) | 3.1 (0.7–15.0) | 34 | 29 (85.3) | 2.4 (0.7–8.1) | 1.4 (0.3–6.9) |
| No treatment | 48 | 34 (70.8) | 31 | 22 (71.0) | ||||
| Age ≥67 yr | 48 | 37 (77.1) | 0.5 (0.2–1.5) | 0.4 (0.1–1.3) | 32 | 25 (78.1) | 1.0 (0.3–3.1) | 0.9 (0.3–3.0) |
| Age <67 yr | 45 | 39 (86.7) | 33 | 26 (78.8) | ||||
| Female sex | 64 | 56 (87.5) | 3.2 (1.1–9.3) | 2.1 (0.5–8.4) | 53 | 44 (83.0) | 3.5 (0.9–13.5) | 2.4 (0.4–13.3) |
| Male sex | 29 | 20 (69.0) | 12 | 7 (58.3) | ||||
| COPD | 22 | 18 (81.8) | 1.0 (0.3–3.5) | 1.4 (0.3–6.2) | 13 | 9 (69.2) | 0.5 (0.1–2.1) | 0.7 (0.2–3.4) |
| No COPD | 71 | 58 (81.7) | 52 | 42 (80.8) | ||||
| Bronchiectasis† | 39 | 35 (89.7) | 2.8 (0.8–9.3) | 1.6 (0.3–7.4) | 29 | 25 (86.2) | 2.4 (0.7–8.7) | 1.4 (0.3–6.7) |
| No bronchiectasis | 54 | 41 (75.9) | 36 | 26 (72.2) | ||||
| Any steroid use‡ | 20 | 16 (80.0) | 0.9 (0.2–3.0) | 1.0 (0.2–4.1) | 14 | 11 (78.6) | 1.0 (0.2–4.3) | 1.2 (0.2–6.0) |
| No steroid use | 73 | 60 (82.2) | 51 | 40 (78.4) | ||||
Definition of abbreviations: AOR = adjusted odds ratio; COPD = chronic obstructive pulmonary disease; OR = odds ratio.
Numbers are count (percent) except as noted. Boldface type indicates P < 0.05.
American Thoracic Society/Infectious Diseases Society of America pulmonary nontuberculous mycobacteria disease criteria (4).
Bronchiectasis noted on computed tomographic scan report or physician diagnosis recorded.
Use of inhaled corticosteroids or oral prednisone.