Table 1.
Characteristics of patients identified by diagnostic code-based algorithms and randomly selected samples used for algorithm validation
| IPF Algorithm* |
IIP Algorithm† |
|||||
|---|---|---|---|---|---|---|
| All Subjects, 2000–2014 (n = 2,608) | All Subjects, 2008–2014 (n = 993) | Validation Sample 1, 2008–2014 (n = 75) | Validation Sample 2, 2008–2014 (n = 75) | All Subjects, 2000–2014 (n = 16,731) | Validation Sample, 2000–2014 (n = 75) | |
| Mean age, yr (SD) | 72.6 (11.6) | 72.6 (11.8) | 73.7 (10.6) | 80.0 (9.5) | 74.6 (10.8) | 73.2 (10.9) |
| Age group, yr, n (%) | ||||||
| <55 | 199 (8%) | 73 (7%) | 3 (4%) | 1 (1%) | 885 (5%) | 2 (3%) |
| 55–59 | 138 (5%) | 58 (6%) | 4 (5%) | 4 (5%) | 915 (5%) | 8 (11%) |
| 60–64 | 239 (9%) | 102 (10%) | 10 (13%) | 2 (3%) | 1,483 (9%) | 9 (12%) |
| 65–69 | 344 (13%) | 137 (14%) | 12 (16%) | 2 (3%) | 2,033 (12%) | 8 (11%) |
| 70–74 | 431 (16%) | 152 (15%) | 11 (15%) | 9 (12%) | 2,412 (14%) | 11 (15%) |
| 75–79 | 467 (18%) | 159 (16%) | 14 (19%) | 10 (13%) | 2,836 (17%) | 13 (17%) |
| >80 | 790 (30%) | 312 (31%) | 21 (28%) | 47 (63%) | 6,167 (37%) | 24 (32%) |
| Sex, n (%) | ||||||
| Male | 1,446 (55%) | 574 (58%) | 39 (52%) | 49 (65%) | 8,149 (49%) | 30 (40%) |
| Female | 1,161 (45%) | 419 (42%) | 36 (48%) | 26 (35%) | 8,582 (51%) | 45 (60%) |
| Race, n (%) | ||||||
| White | 1,735 (67%) | 617 (62%) | 42 (56%) | 59 (79%) | 11,359 (68%) | 50 (67%) |
| Black | 140 (5%) | 50 (5%) | 3 (4%) | 2 (3%) | 950 (6%) | 4 (5%) |
| Asian | 180 (7%) | 98 (10%) | 8 (11%) | 7 (9%) | 1,414 (8%) | 9 (12%) |
| Hispanic | 371 (14%) | 156 (16%) | 14 (19%) | 6 (8%) | 1,885 (11%) | 7 (9%) |
| Other | 182 (7%) | 72 (7%) | 8 (11%) | 1 (1%) | 1,123 (7%) | 5 (7%) |
Definition of abbreviations: ICD-9 = International Classification of Diseases, Ninth Revision; ICD-9-CM = International Classification of Diseases, Ninth Revision, Clinical Modification; IIP = idiopathic interstitial pneumonia; IPF = idiopathic pulmonary fibrosis.
The IPF algorithm requires being older than 18 years of age, having at least one diagnostic claim for ICD-9 code 516.3 or ICD-9-CM code 516.31, and exclusion of alternative interstitial lung disease diagnostic claims.
The IIP algorithm requires being older than 50 years of age; having at least one claim for the ICD-9 codes 515, 516.3, or 516.31; and exclusion of alternative interstitial lung disease diagnostic claims.