Table 5.

Estimation of hazard ratio, 95% confidence interval, and P value from cause-specific hazards models of time from indwelling pleural catheter insertion to pleurodesis

Event	Covariate	Univariate Model				Multivariable Model
		HR	95% CI		P Value	HR	95% CI		P Value
Pleurodesis	Log time to IPC	0.984	0.873	1.108	0.7855	0.966	0.827	1.129	0.6654
	ANC
	≤0.5	1.000				1.000
	>0.5	0.689	0.365	1.301	0.2511	0.953	0.395	2.299	0.9147
	Age at IPC	0.995	0.979	1.010	0.4887	0.986	0.967	1.005	0.1564
	Male sex	1.027	0.666	1.583	0.9044	0.873	0.511	1.493	0.6209
	Hematologic group				0.0077*				0.0020*
	Lymphoma	1.000				1.000
	Acute leukemia	2.411	1.314	4.426	0.0045	2.368	1.111	5.048	0.0255
	Chronic leukemia	1.312	0.754	2.283	0.3365	1.596	0.764	3.335	0.2134
	Multiple myeloma	0.494	0.197	1.242	0.1340	0.268	0.095	0.754	0.0126
	Stem cell† transplant	1.105	0.612	1.995	0.7413	1.686	0.819	3.475	0.1564
	Platelets				0.9960*				0.5043*
	>50 K/μl	1.000				1.000
	Between 20 K/μl–50 K/μl	0.970	0.500	1.884	0.9284	0.599	0.246	1.459	0.2592
	≤20 K/μl	0.992	0.240	4.093	0.9906	1.181	0.260	5.351	0.8295
	Creatinine
	≤1.5 mg/dl	1.000				1.000
	>1.5 mg/dl	1.153	0.530	2.509	0.7197	2.182	0.849	5.606	0.1050
	Etiology
	Nonmalignant	1.000				1.000
	Malignant	0.725	0.421	1.250	0.2472	0.691	0.344	1.389	0.2992
	Chylothorax
	Not present	1.000				1.000
	Present	0.802	0.466	1.380	0.4247	0.648	0.341	1.230	0.1844

Definition of abbreviations: ANC = absolute neutrophil count; CI = confidence interval; HR = hazard ratio; IPC = indwelling pleural catheter.

^*Overall effect of the covariate.

^†History of autologous or allogeneic stem cell transplantation.